Prevention of Biopsychosocial Complications in Adolescents who Consume Addictive Substances: Integrative Review
Main Article Content
Abstract
Introduction: the beginning of the consumption of addictive substances in adolescents has severe implications for their long-term health, enabling the development of diseases, emotional problems and social isolation. The adoption of consumer habits can lead to abuse and dependence and have a biopsychosocial impact.
Objective: identify the main biopsychosocial complications in adolescents who consume addictive substances.
Method: the methodology proposed by Toronto & Remington (2020) was used; the process of evaluation and selection of articles with a quantitative approach, the eligibility criteria instrument for the selection of research articles (ICrESAI) was used and the evaluation of randomized clinical trials using a checklist with consolidated standards for trial reporting (Consort).
Results: 18 articles were analyzed, ten of them RCTs, seven RCT pilot studies, and one longitudinal quantitative study.
Discussion and conclusions: three intervention approaches to the consumption of addictive substances in adolescents were found, which respond to biological, psychological and social complications that impact the growth and development of adolescents. The consumption of alcohol, marijuana and nicotine is related to the impact on mental health, which leads to an increase in offending behavior, car accidents and self-inflicted violence. There is a need to structure prevention interventions against the consumption of addictive substances with an impact on mitigating complications that compromise the mental health of adolescents.
Article Details

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
References
Albertos, A., Osorio, A., & Beltramo, C. (2020). Adolescentes y ocio: desarrollo positivo y transición hacia la vida adulta. Educación y Educadores, 23(2), 201–210. https://doi.org/10.5294/edu.2020.23.2.3
Arnaud, N., Baldus, C., Laurenz, L. J., Bröning, S., Brandt, M., Kunze, S., Austermann, M., Zimmermann, L., Daubmann, A., Thomasius, R., Nees, F., Prignitz, M., Guldner, S., Flor, H., Sack, P. M., Wegscheider, K., Zapf, A., Meibert, P., Michalak, J., … Coombs, L. (2020). Does a mindfulness-augmented version of the German Strengthening Families Program reduce substance use in adolescents? Study protocol for a randomized controlled trial. Trials, 21(1). https://doi.org/10.1186/s13063-020-4065-1
Boutron, I., Altman, D. G., Moher, D., Schulz, K. F., Ravaud, P., & CONSORT NPT Group (2017). CONSORT Statement for Randomized Trials of Nonpharmacologic Treatments: A 2017 Update and a CONSORT Extension for Nonpharmacologic Trial Abstracts. Annals of internal medicine, 167(1), 40–47. https://doi.org/10.7326/M17-0046
Berasaluce, M., Martín-Turrero, I., Valiente, R., Martínez-Manrique, L., Sandín-Vázquez, M., & Sureda, X. (2023). Urban and social determinants of alcohol and tobacco consumption among adolescents in Madrid. Gaceta Sanitaria, 37(102336), 102336. https://doi.org/10.1016/j.gaceta.2023.102336
Braitman, A. L., Strowger, M., Lau-Barraco, C., Shipley, J. L., Kelley, M. L., & Carey, K. B. (2021). Examining the added value of harm reduction strategies to emailed boosters to extend the effects of online interventions for college drinkers. Psychology of Addictive Behaviors. 36(6), 635–647. https://doi.org/10.1037/adb0000755
Brown, L. D., Bandiera, F. C., & Harrell, M. B. (2019). Cluster Randomized Trial of Teens Against Tobacco Use: Youth Empowerment for Tobacco Control in El Paso, Texas. American Journal of Preventive Medicine, 57(5), 592–600. https://doi.org/10.1016/j.amepre.2019.06.013
Cacho Becerra, Z. V., Silva Balarezo, M. G., & Yengle Ruíz, C. (2019). El desarrollo de habilidades sociales como vía de prevención y reducción de conductas de riesgo en la adolescencia. Transformación, 15(2), 186–205. http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S2077-29552019000200186&lng=es&tlng=es
Conde, K., Brandariz, R. A., Lichtenberger, A., & Cremonte, M. (2018). The effectiveness of a brief intervention for reducing adolescent alcohol consumption. Revista Ciencias de la Salud, 16(3), 409–423. https://doi.org/10.12804/revistas.urosario.edu.co/revsalud/a.7261
Conner, M., Grogan, S., Simms-Ellis, R., Flett, K., Sykes-Muskett, B., Cowap, L., Lawton, R., Armitage, C., Meads, D., Schmitt, L., Torgerson, C., West, R., & Siddiqi, K. (2020). Evidence that an intervention weakens the relationship between adolescent electronic cigarette use and tobacco smoking: A 24-month prospective study. Tobacco Control, 29(4), 425–431. https://doi.org/10.1136/tobaccocontrol-2018-054905
Corona, R., Dvorsky, M. R., Romo, S., Parks, A. M., Bourchtein, E., Smith, Z. R., Avila, M., & Langberg, J. (2020). Integrating Tobacco Prevention Skills into an Evidence-Based Intervention for Adolescents with ADHD: Results from a Pilot Efficacy Randomized Controlled Trial. Journal of Abnormal Child Psychology, 48(11), 1439–1453. https://doi.org/10.1007/s10802-020-00689-6
Deluca, P., Coulton, S., Alam, M. F., Boniface, S., Donoghue, K., Gilvarry, E., Kaner, E., Lynch, E., Maconochie, I., McArdle, P., McGovern, R., Newbury-Birch, D., Patton, R., Pellat-Higgins, T., Phillips, C., Phillips, T., Pockett, R. D., Russell, I. T., Strang, J., & Drummond, C. (2022). Effectiveness and cost-effectiveness of face-to-face and electronic brief interventions versus screening alone to reduce alcohol consumption among high-risk adolescents presenting to emergency departments: three-arm pragmatic randomized trial (SIPS Junior high risk trial). Addiction, 117(8), 2200–2214. https://doi.org/10.1111/add.15884
Falke, G. O., & Pellegrino, J. A. (2020). Salud integral del joven y del adolescente. Medicina preventiva y social. Revista de la Asociación Médica Argentina, 133(4), 24–29.
Fierro Herrera, C. Y., Guzmán Facundo, F. R., & Pillon, S. C. (2023). Factores de riesgo y protección del consumo de drogas ilícitas en adolescentes latinoamericanos. Revista Internacional de Investigación en Adicciones, 9(1), 101–112. https://doi.org/10.28931/riiad.2023.1.10
Gómez-Ortega, O. R., & Amaya-Rey, M. C. del P. (2013). ICrESAI-IMeCI: instrumentos para elegir y evaluar artículos científicos para la investigación y la práctica basada en evidencia. Aquichan, 13(3), 407–420. https://www.redalyc.org/articulo.oa?id=74130042009
Hauser, S. R., Waeiss, R. A., Deehan, G. A., Engleman, E. A., Bell, R. L., & Rodd, Z. A. (2023). Adolescent alcohol and nicotine exposure alters the adult response to alcohol use. Advances in Drug and Alcohol Research, 3. https://doi.org/10.3389/adar.2023.11880
Hodder, R. K., Freund, M., Bowman, J., Wolfenden, L., Campbell, E., Dray, J., Lecathelinais, C., Oldmeadow, C., Attia, J., & Wiggers, J. (2018). Effectiveness of a pragmatic school-based universal resilience intervention in reducing tobacco, alcohol and illicit substance use in a population of adolescents: Cluster-randomised controlled trial. BMJ Open, 7(8). https://doi.org/10.1136/bmjopen-2017-016060
Huberty, J., Green, J., Glissmann, C., Larkey, L., Puzia, M., & Lee, C. (2019). Efficacy of the mindfulness meditation mobile app “calm” to reduce stress among college students: Randomized controlled trial. JMIR mHealth and uHealth, 7(6). https://doi.org/10.2196/14273
Isensee, B., & Hanewinkel, R. (2021). “Aktion Glasklar“– eine Informations- und Sensibilisierungskampagne zur Alkoholprävention im Jugendalter ["Aktion Glasklar"-an information and awareness campaign to prevent alcohol consumption in adolescence]. Bundesgesundheitsblatt, 64(6), 733–736. https://doi.org/10.1007/s00103-021-03340-x
Kaur, S., Kaur, M., & Kumar, R. (2022). Health promotion intervention to prevent risk factors of chronic diseases: Protocol for a cluster randomized controlled trial among adolescents in school settings of Chandigarh (India). PLoS ONE, 17(2), e0263584. https://doi.org/10.1371/journal.pone.0263584
Kazemi, D. M., Borsari, B., Levine, M. J., Li, S., Shehab, M., Fang, F., & Norona, J. C. (2020). Effectiveness of a theory-based mHealth intervention for high-risk drinking in college students. Substance Use & Misuse, 55(10), 1667–1676. https://doi.org/10.1080/10826084.2020.1756851
Meacham, M. C., Ramo, D. E., Prochaska, J. J., Maier, L. J., Delucchi, K. L., Kaur, M., & Satre, D. D. (2021). A Facebook intervention to address cigarette smoking and heavy episodic drinking: A pilot randomized controlled trial. Journal of Substance Abuse Treatment, 122. https://doi.org/10.1016/j.jsat.2020.108211
Osei Asibey, B., Marjadi, B., & Conroy, E. (2023). Alcohol, tobacco and drug use among adults experiencing homelessness in Accra, Ghana: A cross-sectional study of risk levels and associated factors. PloS One, 18(3), e0281107. https://doi.org/10.1371/journal.pone.0281107
Rao, A., Unnikrishnan, B., Mithra, P., Nandini, M., Shenoy, R., & Rungta, N. (2019). Effectiveness of a school-based “tobacco free” intervention on adolescents’ knowledge and exposure to second hand tobacco smoke - A multiphase study. Asian Pacific Journal of Cancer Prevention, 20(12), 3533–3537. https://doi.org/10.31557/APJCP.2019.20.12.3533
Rocha, R. P., De Oliveira Galvão, P. P., van der Meer Sanchez, Z., Rebouças, L. N., De Castro Júnior, A. R., Dos Santos, L. E. S., Martins, M. C., Da Costa Pinheiro, P. N., Vieira, N. F. C., & Gubert, F. D. A. (2022). Body dissatisfaction, drug use, and associated factors among adolescents in three Brazilian cities. Revista Latino-Americana de Enfermagem, 30(Special Issue). https://doi.org/10.1590/1518-8345.6163.3663
Ruffolo, J., Frie, J. A., Thorpe, H. H. A., Talhat, M. A., & Khokhar, J. Y. (2022). Alcohol and vaporized nicotine co-exposure during adolescence contribute differentially to sex-specific behavioral effects in adulthood. Nicotine & Tobacco Research, 24(8), 1177–1185. https://doi.org/10.1093/ntr/ntab250
Sharma, S. R., Matheson, A., Lambrick, D., Faulkner, J., Lounsbury, D. W., Vaidya, A., & Page, R. (2020). The role of tobacco and alcohol use in the interaction of social determinants of non-communicable diseases in Nepal: a systems perspective. BMC Public Health, 20(1). https://doi.org/10.1186/s12889-020-09446-2
Spirito, A., Nestor, B., Massing-Schaffer, M., Esposito-Smythers, C., Stout, R., Frazier, E., Gomez, J., Graves, H., Yen, S., Hunt, J., & Wolff, J. (2021). Predictors and moderators of marijuana and heavy alcohol use outcomes in adolescents treated for co-occurring substance use and psychiatric disorders in a randomized controlled trial. Journal of Substance Abuse Treatment, 131, 108536. https://doi.org/10.1016/j.jsat.2021.108536
Springer, A. E., Harrell, M. B., Martínez Gomensoro, L., Traversa Fresco, M., Rogers, S., Florines, M., Moreno, V., Lee, J., Perry, C. L., Bianco, E., & Estol, D. (2020). ¡Activate Ya! Co-learning about school-based tobacco prevention and physical activity promotion in secondary school students in Uruguay. Global Health Promotion, 27(2), 63–73. https://doi.org/10.1177/1757975918813049
Toronto, C. E., & Remington, R. (2020). A Step-by-Step Guide to Conducting an Integrative Review.https://doi.org/ https://doi.org/10.1007/978-3-030-37504-1
Valente de Almeida, S., Correa, R., & Gonçalves, J. (2022). Can Intersectoral Interventions Reduce Substance Use in Adolescence? Evidence From a Multicentre Randomized Controlled Study. International Journal of Public Health, 67. https://doi.org/10.3389/ijph.2022.1604677